Singulair: Proficient drug for Asthma treatment 

Asthma is referred to as a chronic disease that affects the airways in the lungs. Airways are tube-like structures that carry air to and from the lungs. In the condition of asthma, the airways may become inflamed and sometimes blocked. When you inhale, it prevents air from passing through your airways, causing shortness of breath.

Types of Asthma:

The four main categories of asthma, a chronic respiratory disease that makes breathing difficult, are:

  • Intermittent
  • Mild persistent
  • Moderate persistent
  • Severe persistent

Symptoms of Asthma:

Some of the commonly seen symptoms of asthma are as follows:

  • Coughing
  • Wheezing, a whistling sound when you breathe
  • Shortness of breath
  • Tightness, pain or pressure in your chest
  • Blue fingers and lips
  • Fainting 
  • Trouble sleeping due to breathing issues

Causes of Asthma:

Some commonly observed causes of asthma are as given:

  • Respiratory infections and colds
  • Allergens
  • Cigarettes Smoking
  • Air pollution
  • Exposure to cold air
  • Sudden changes in temperature
  • Stress
  • Exercise 
  • Environmental factors

Ventolin HFA: Proficient Inhaler for Asthma treatment 

Albuterol belongs to the SABA class (short-acting beta agonist) and works as a bronchodilator by relaxing the muscles in the airways of the lungs, which increases airflow in the lungs. This increased airflow makes it easier for the patient to breathe. Ventolin HFA is an inhalation solution that contains albuterol sulfate as the active ingredient and is used to treat asthma. Ventolin HFA is a quick-relief medicine as an inhalation solution. Ventolin HFA is a drug that contains albuterol sulfate, its generic name.

Treatment of Asthma:

Singulair comes under a class of drugs called leukotriene receptor antagonists.  Singulair is a brand name for montelukast sodium which is its generic name. Singulair (montelukast) is an oral medication used to treat allergies as well as long-term treatment of allergic asthma. It works by blocking some natural substances (leukotrienes) that can cause or worsen asthma and allergies.  It makes breathing easier by reducing inflammation in the airways of the lungs. It does not work as well as other commonly used asthma inhalers.  Singulair usually supports the treatment of asthma that is difficult to control.

Singulair Uses :

Some common and important Singulair Uses are written as follows:

Montelukast is used in treatment of:

  • Asthma 
  • Bronchospasm.
  • Montelukast also reduces the symptoms of hay fever and allergic Rhinitis.
  • Exercise induced Bronchoconstriction. 
  • Seasonal and year-round allergies

Singulair Dosage:

  • Singulair Dosage in Paediatrics for Asthma maintenance:

From 12 to 23 months old:

One sachet of 4mg granules taken orally once in a day

From 2 to 5 years old:

One sachet of granules taken orally once in a day or 5mg chewable tablet

From 6 to 14 years old:

5 mg chewable tablet taken orally once in a day

From 15 years or older:

10 mg tablet taken orally once in a day

  • Singulair Dosage in Adults for Asthma maintenance:

10 mg tablet orally taken once in a day

  • Singulair Dosage in Paediatrics for Bronchospasm Prophylaxis:

From 6 to 14 years old:

5 mg chewable tablet taken orally once in a day

From 15 years or older:

10 mg tablet taken orally once in a day

  • Singulair Dosage in Adults for Bronchospasm Prophylaxis:

10 mg tablet taken orally once in a day at least 2 hours before exercise

  • Singulair Dosage in Paediatrics for Allergic Rhinitis:
  • For treatment of Seasonal Allergies:

From 2 to 5 years old:

4 mg chewable tablet or one sachet of 4 mg oral granules once in a day

From 6 to 14 years old:

5 mg chewable tablet taken orally once in a day

From 15 years or older:

10 mg tablet taken orally once in a day

  • For treatment of Perennial Allergic Rhinitis:

From 6 to 23 months old:

One sachet of granules (4 mg) taken orally once in a day

From 2 to 5 years old:

4 mg chewable tablet taken orally once in a day

From 6 to 14 years old:

5 mg chewable tablet taken orally once in  a day

From 15 years or older:

10 mg tablet taken orally once in a day

  • Singulair Dosage in Adults for Allergic Rhinitis:

10 mg tablet taken orally once in a day

Singulair Interactions:

Drug interactions can make changes in how your medications work or increase the risk of serious side effects. Always tell your doctor and pharmacist about any other drugs or supplements (prescription drugs, vitamins, dietary supplements or herbs) you are currently taking. All possible drug interactions are not mentioned in this document. Some of Singulair interactions are as follows:

Using these medicines with Singulair can cause side effects so before taking tell your doctor so he will change the medicine or change the dose if necessary:

  • Dasabuvir
  • Leflunomide
  • Pixantrone
  • Teriflunomide
  • Gemfibrozil
  • Prednisone
  • istradefylline
  • itraconazole
  • ketoconazole
  • letermovir
  • levoketoconazole

Singulair Side Effects:

Montelukast can cause some side effects too. This document does not include all possible side effects, 2Some of the common Singulair side effects are given as:

Commonly observed  Singulair side effects include:

Headache 

Abdominal pain 

Heartburn 

Other  Singulair side effects include:

  • Rash
  • Fever
  • Fatigue
  • Dizzines

Less common side effects include:

  • Bloody nose
  • general feeling of discomfort or illness
  • joint pain
  • sweating

Singulair Precautions and Warnings:

Talk to your doctor or pharmacist if you have any allergies before taking montelukast. Or if you have another allergy. These products may contain inactive ingredients that may cause allergies or other problems. Ask your pharmacist for more information. Before taking this medication, tell your doctor or pharmacist your medical history, especially of, Liver disease, mental/emotional problems (eg, anxiety, depression, suicidal thoughts). Before surgery, tell your doctor or dentist about all the products you use (including prescription products and herbs). Chewable tablets may contain aspartame. If you have phenylketonuria (PKU) or other conditions that require you to limit aspartame (or phenylalanine) in your diet, talk to your doctor or pharmacist about how to use this medicine safely. During pregnancy, this medicine should be used only when necessary. Discuss with your doctor about all the benefits and adverse effects. The drug passes into breast milk. Consult your doctor before breast-feeding.

Singulair Pros and Cons:

Pros:

  • Singulair(montelukast) has to be taken only once per day.
  • It is a good option for children as well as for those who have difficulty in using inhalers.
  • It is available as chewable tablets as well as in granules.

Cons:

  • it can’t be used in an emergency asthma attack but some other inhalers can.
  • The use of Singulair(montelukast) can cause serious mental health disturbances eg. Hallucinations, agitation, dream disorders etc.

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